Services

Biomarker Assays

Cardinal Bioresearch offers a broad range of biomarkers ranging from general chemistry tests including, glucose, beta hydroxybutyrate, liver and renal function to immunoassays for Vitamin D, bone markers, cytokines, adipokines, neuropeptides, steroids, to specialised immunoassays.  Whenever possible we utilise our Luminex based multiplexed assays to provide you with an efficient and economical service.  Our test list is growing all the time but here is a list of some of the immunoassays and multiplexed assays available - Download PDF.

We understand that most research projects need careful budgeting. Due to the large volume of assays we perform, we have negotiated reduced reagent costs with some of our suppliers and can pass these savings onto our customers.

In our experience, most researchers are interested in the latest biomarkers shown to be associated with a particular condition. Please contact us to discuss your needs and benefit from our experience in choosing the right biomarker panel for your study.

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Myriad RBM Inc

Cardinal Bioresearch is pleased to act as the Australian distributor for Myriad RBM Inc. Myriad RBM, Inc. is the world’s leading multiplexed immunoassay testing laboratory, providing comprehensive protein biomarker services based on its Multi-Analyte Profiling (MAP) platform. This platform provides pre-clinical and clinical researchers with reproducible and quantitative data for a few or hundreds of proteins in a cost-effective manner.  All services are performed in their CLIA certified laboratory.  As a guide to drug development researchers, Myriad RBM also offers strategic biomarker services that include companion diagnostics, custom assay development, co-sponsored research programs, and innovative cell culture products.  Myriad RBM’s biomarker testing laboratory is a wholly owned subsidiary of Myriad Genetics, Inc. (MYGN).  

Myriad RBM services include a routine tesing panel of over 300 biomarkers and is ideal for those wanting to use a wide brush approach to identify novel biomarkers.  Please visit their website  http://rbm.myriad.com/products-services/humanmap-services/human-discoverymap/ for more information

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Cell Signalling Assays and transcription factor assays

Our cell signalling assays utilise the Luminex based multiplex assays enabling the identification of multiple phospho-proteins from multiple pathways all in the same reaction. For an example of the targets available see the link to the MAPmate panels and the EpiQuant panels.

Our transcription factor assay is an ideal start to any cell signalling project as if can identify which transcription factors have been activated and have translocated into the nucleus. We perform two multiplex assays. Panel 1 covers 41 transcription factors and panel 2 covers 44 transcription factors. For more information see the Panomics Website.

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Targeted mRNA quantitation / Microarray validation

Targeted mRNA quatification has never been easier.  All we need is for you to add your sample to our lysis buffer and send them to us. We do the rest. We can assay up to 36 targets in the same multiplexed assay. So your house keeping genes act as the internal reference. This makes for less error and better results. If you need more information about the technology we use you can go the Panomics Website.

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Targeted DNA Copy number variations / Microarray validation

We utilise the Panomics Quantigene Plex DNA assay to quantitate copy number variations. This method multiplexes up 33 targets in one assays and uses bDNA technology. The method is compatible with plant and animal tissues, FFPE tissue sections, whole blood, cultured cells, isolated DNA and more. For more information see the Panomics Website.

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Microarrays/Next Generation Sequencing

 

Otogenetics Corporation provide next generation sequencing services including predefined disease and pathway genes, human and mouse exomes, epigenetic profiling, custom targeted genes and RNA-seq. Otogenetics cost efficient high through put work flow has allowed Otogenetics to provide an unbeatable triple guarantee. They will guarantee coverage, guarantee to bet any competitors written quote and guarantee turn around time. www.otogenetics.com

Expression Analysis provides whole genome to focused set gene expression and genotyping assays along with DNA sequencings services, sequence enrichment technologies and bioinformatics support.  Platforms utilized include Affymetrix GeneChip® and GeneTitan®, Agilent Sure Select, Applied Biosystems’ Taqman, Fluidigm Access Arrays, Illumina BeadChip®, iScan and Genome Analyzer, RainDance Technologies RDT 1000 and, the Pacific Biosciences™ PacBio RS.  Expression Analysis offers solutions for challenging specimens such as whole blood and FFPE tissues, as well as nucleic acid isolation and data analysis services.  Our quality system follows CLSI guidelines and our CLIA-registered laboratory supports GLP compliance. www.expressionanalysis.com

 

CeGaT, Center for Genomics and Transcriptomics, is a service provider for DNA and RNA sequencing of humans, animals, plants, and microorganisms. We use the latest available technologies and apply

Depending on the particular project, we decipher single Genes, Exomes, Transcriptomes, Epigenomes, microRNA or complete Genomes.

CeGaT is an accredited Molecular Human Genetic Diagnostics Laboratory according to DIN EN ISO 15189:2007.   www.cegat.de

                         

 

Fatty Acid Profiling

 

 

Along with the HS-Omega-3 Index, the full fatty acid profile is listed for 26 fatty acids by group – Omega-3 Fatty Acids, Omega-6 Fatty Acids, cis-Monounsaturated Fatty Acids, Saturated Fatty Acids, and Trans Fatty Acids. We also list the Omega-6:Omega-3 ratio and Arachidonic:EPA ratio. These are provided for reference only.

We offer two collection methods, blood tube or finger stick, which yield two different sample types, red blood cell (RBC) or dried blood spot (DBS), respectively. Both the RBC and the DBS tests include the HS-Omega-3 Index® as well as the full fatty acid profile.  www.omegaquant.com

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HPLC and Mass Spectrometry

We have a range of HPLC and Mass spectrometry assays routinely available through our collaboration with a government testing laboratory.  Custom assays are also available, just send us your test and if possible your method.

Routine tests include the following:

  • Immunosuppressants , Steroids , Plasma Metanephrines , Vitamin D, Mycophenolate
  • Urine Biogenic Amines Plasma Catacholamines, Platelet Serotonin
  • Lamotrigine (Monday, Wednesday and Friday)
  • Antibiotics - Ampicillin, Benzyl Penicillin, Ceftazidime, Ceftriaxone, Cephalothin, Cephazolin, Dicloxacillin, Ertapenem, Flucloxacillin, Meropenem, Piperacillin and Ticarcillin
  • Antifungals – Posaconazole and Voriconazole , Ciprofloxacillin, Acyclovir/Gancyclovir, Atracurium
  • HIV Antiproteases - Amprenavir, Efavirenz, Indinavir, Lopininavir, Nelfinavir, Nevirapine, Ritonavir, Saquinavir, Ivermectin, Clozapines
  • Benzodiazepines - Clonazepam, Clobazams and Diazepam
  • 5FC
  • Quinine, Thiopentone, Warfarin, Olazapine
  • Amiodarone, Chlorpromazine, Flecainide, Itraconazole, Lignocaine, Mexiletine, Procainamide, Perhexiline,
  • Sotalol, Thiocynate, Thioridazine, Isoniazide Screening, Sulthiame, Ethosuximide, Rifampicin Screening, Sulphonylurea, Streptomycin
  • Vitamin A&E and Carotenoids, Ubiquinone, 6-Thioguainines, Busulphan, Chloramphenicol, HbA1c, Thiamines, Pyridinolines
  • Amino Acids, Phenylalanine Screen, Cystinuria Profile
  • Porphyrins, PBG Deaminase
  • Pterins
  • Neurotransmitters
  • Folates

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Custom Assay Development

Cardinal Bioresearch is able to offer custom immunoassay services. Please contact us and tell us your project ideas. Cardinal Bioresearch is also interested in collaborating with groups who believe they have a product with market potential.

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Luminex Training Workshops

Cardinal Bioresearch conducts training seminars and workshops for the Luminex technology. This includes training in commercially developed kit as well as kit development.

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P 04 0153 3930     |     F 07 3343 3345     |     E     |     PO Box 1393 New Farm 4005 QLD Australia